با سلام و عرض ادب. لطف می کنین پاتولوژی رو تفسیر کنین؟ ممنونم Pathology Report Clinical data: CT-scan findings: There is a cystic lesion with irregular border and internal septation and peripheral enhancement at right aspect of pelvic cavity resulting ureteral compression and stenosis at ureteral level. There is a 4 cm defect in anterior abdominal wall with herniation Core needle biopsy pathology diagnosis: - Unclassifiable small epithelial cell tumor with immunoreactivity of sex cord stromal tumor - Negative for lymphoma - Negative for sarcoma - Negative for germ cell tumor Macroscopy: Specimens received in formalin in two containers as follows: A- Labeled as pelvic mass is an irregularly shaped tumoral tissue, partially covered by serosa, measuring 5.5x3.5x3.5 cm. Attached to the mass is vermiform appendix measuring 5.5 cm in length and 0.8 cm in diameter, other end of appendix closed by clips. Mesoappendix measuring 4.5x2x0.7 cm. Sections show tan- yellow tumoral tissue with necrotic areas extending to surgical margin and beneath the serosal surface. Appendix lumen is obliterated with fibrofatty tissue. There are multiple clips near location of appendix to tumoral tissue with surrounding fibrosis, seems related to prior surgery Representative sections submitted in 9 cassettes as follows: #A1= appendix end with clips, #A2= appendix at attachment site to tumor, #A3-A7= tumor, #A8-A9= adipose tissue and tumor B-Designated as incisional hernia sac is a flat shaped adipose tissue, partially covered by serosa measuring 8x6 cm in diameter and 1.5 cm in thickness. No lesion identified in serial section. Representative sections submitted in 2 cassettes Microscopy: A) Sections show smooth muscle layer covered by serosa and infiltrated by malignant neoplasma forming nests, sheets and trabecular patterns with thick fibrous trabeculae. The tumor composed of epithelioid cells with moderate eosinophilic cytoplasm, moderately atypical nuclei with coarse chromatin and prominent nucleoli. Mitotic rate is high. Many necrotic area present in the tumor. See the diagnosis A) for more details B) Histopathologic findings are compatible with following diagnosis. Diagnosis: A-Designated as pelvic mass, resection: - Malignant epithelioid neoplasm infiltrating smooth muscle layer adipose tissue and extending beneath the serosa Surgical margin involved by tumor - Lymphovascular invasion present Appendix present with fibrous obliteration - See the note 1 atology Report B-Designated as incisional hernia, repair: - Fibroadipose tissue, partially covered by mesothelial cells - Negative for malignancy Note: Prior histopathology and IHC report of core needle biopsy with diagnosis of: "Unclassifiable small epithelial cell tumor with immunoreactivity of sex cord stromal tumor" was noted, but that sample may be not representative of the whole tumor, so Immunohistochemical study is necessary in order to reach a definite diagnosis; the patient was duly informed about the importance and necessity of the IHC study, but rejected our recommendation to perform the test.
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